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Dec 13, 2020; Paradise, Nevada, USA; Detailed view of an Indianapolis Colts helmet against the Las Vegas Raiders at Allegiant Stadium. Mandatory Credit: Mark J. Rebilas-USA TODAY Sports

• Colts vs Texans spread: -7.5, Colts
• Colts vs Texans moneyline: Colts (-375)
• Prediction: Colts 27, Texans 17

The Indianapolis Colts simply couldn’t ask for a better way to start their 2022 NFL season. While it will begin things on the road, this is an opportunity for the team to establish some momentum early. Matt Ryan shouldn’t have too much trouble against Houston’s defense and this could be a huge day for Jonathan Taylor.

Related: 2022 NFL power rankings

Let’s take a quick look at the Indianapolis Colts roster for the 2022 season.

Matt Ryan replaces Carson Wentz, taking over as the Indianapolis Colts starting quarterback this season. Ryan is an upgrade, providing far more stability for Frank Reich at the most important position. The Colts’ offensive line also projects to be better in 2022. Indianapolis will be counting on a big leap from Michael Pittman Jr. this year, viewing him as the No.1. receiver. Meanwhile, rookie Alex Pierce should play a prominent role. Of course, this offense will be carried by MVP candidate Jonathan Taylor.

Defensively, while the Colts traded Rock Ya-Sin this offseason this unit should be improved. Stephon Gilmore joins the secondary and Yannick Ngakoue bolters a pass rush that needed help on the edge. Both players should help this be a top-12 defense in 2022, but the departure of defensive coordinator Matt Eberflus is a blow.

Here is the Indianapolis Colts preseason schedule.

Related: Indianapolis Colts training camp schedule

Indianapolis Colts schedule 2022

Here you can find all the information you need on the 2022 Indianapolis Colts schedule. We’ll provide game predictions, betting info and more throughout the season.

• Prediction: Colts 31, Jaguars 20

• Prediction: Chiefs 28, Colts 24

• Prediction: Colts 24, Titans 21

• Prediction: Broncos 31, Colts 27

• Prediction: Colts 27, Jaguars 17

• Prediction: Titans 23, Colts 21

• Prediction: Colts 31, Commanders 17

• Prediction: Colts 20, Patriots 17

• Prediction: Raiders 24, Colts 21

• Prediction: Colts 27, Eagles 21

• Prediction: Colts 23, Steelers 17

• Prediction: Cowboys 28, Colts 27

• Prediction: Colts 35, Vikings 27

• Prediction: Chargers 31, Colts 27

• Prediction: Colts 20, Giants 17

• Prediction: Colts 27, Texans 24

The Colts are coming off a heartbreaking 2021 season. They entered Week 17 with a 9-6 record, one victory away from making the playoffs. However, consecutive losses to the Las Vegas Raiders and Jacksonville Jaguars crushed the Colts’ playoff hopes. Because of the brutal finish, Indianapolis traded Carson Wentz for Day 2 picks and replaced him with Matt Ryan. Indianapolis is favored to win the AFC South in 2022.